Another nootropic or smart drug used by many people today is Exelon. The active substance of Exelon is called Rivastigmine. Rivastigmine belongs to a group of medications called cholinesterase inhibitors. It is mainly used for treating Alzheimer's dementia and dementia due to Parkinson's disease, since its chemicals react with the chemicals in our brain, improving memory and thinking ability.
In case of dementia, certain nerve cells in the brain die, which results in low levels of the neurotransmitter acetylcholine (a substance which allows communication between nerve cells). Rivastigmine works by blocking the enzymes which decompose acetylcholine. By blocking these enzymes, Exelon increases the acetylcholine level in the brain, which in turn helps in reducing the symptoms of Alzheimer's and dementia due to Parkinson's disease.
Exelon is applied in treatments of mild and less severe dementia, as well as progressive brain dysfunction causing damage to intellectual capacity, memory, and behavior. Exactly due to its memory-enhancing effect, it gained popularity among healthy individuals, too, although its off-label use is not recommended by doctors.
Recommendations on Exelon by experts
The medication Exelon must not be used if you are allergic to Rivastigmine or any other substance of this drug. Notify your doctor and stop using Exelon if you experience any of these symptoms: A skin reaction that spreads outside the surface covered by a patch, a noticeable local reaction - blisters, a skin inflammation, swelling, or in case of absence of any betterment about 48 hours after taking off the patch.
Also, when taking Exelon, take special care if you have or had any of these symptoms:
- arrhythmia (irregular heartbeat);
- an active stomach ulcer;
- trouble urinating;
- asthma or a severe respiratory illness;
- damaged kidney function;
- damaged liver function;
- loss of body mass;
- gastro-intestinal reactions, such as nausea, vomiting and diarrhea (dehydration (excessive fluid loss) may result as a consequence of long-term vomiting or diarrhea).
If any of the above applies to you, do not neglect those symptoms, stop taking the drug and immediately call your doctor. If you haven't taken the medication Exelon for a couple of days, do not take the next dose before consulting your doctor.
Interaction of Exelon with other drugs
You should notify your doctor if you are taking, or have recently taken, or would take other medications, including the ones given out without doctor's prescription.
Exelon must not be given at the same time with other medications that have a similar effect as Exelon. This includes all nootropics and stimulant drugs, besides other stimulant substances. Exelon can also interact with anticholinergic medications (used for treating stomach cramps or spasm, Parkinson's disease, and nausea during travel).
Beware of surgical procedures while on Exelon, since it augments certain muscle relaxants' effect when using anesthesia. Tell your doctor if you need to have a surgery done.
When not to take Exelon?
Do not take Exelon if you are pregnant or breastfeeding, and do not drive or perform other acts that demand your full concentration and attention, since Exelon can cause dizziness and sleepiness, mostly in the beginning of the therapy or if you increase the dosage. Children and adolescents should not take this drug, either.
Take Exelon only after consulting your doctor
A therapy with Exelon usually begins with a small dosage, and it must be individually estimated by your doctor. The largest dose taken is 6 mg twice a day.
If you accidentally took more Exelon than you are supposed to, inform your doctor. You might need medical help. Some people who take more Exelon than needed can experience nausea, vomiting, diarrhea, high blood pressure, and hallucinations. It can also lead to a slowing of the heartbeat and unconsciousness.
Never take a double dose to make up for the missed one.
Numerous negative effects of Exelon and other nootropics
One out of ten people taking Exelon will experience dizziness and loss of appetite. Other possible effects with the same frequency of appearance include:
- a sense of fear (anxiety);
- loss of body mass ;
- stomach pain;
- weakness or fatigue;
- a feeling of poor general condition;
- tremor or confusion.
Less often you might experience depression, trouble sleeping, unconsciousness and accident falls, and changes in liver functioning. These symptoms affect one person out of hundred.
Other rarer negative effects that might appear in one out of 1000 people include chest pain, rash, epileptic seizures, and stomach or intestine ulcer, as well as high blood pressure, urinary tract infections, hallucinations, heartbeat issues, like rapid or slowed heartbeat, intestinal bleeding - manifested as blood in excrement or blood during vomiting, pancreatic inflammation - manifested as sharp upper chest pain, commonly followed by nausea and vomiting, then, worsening of Parkinson's disease symptoms such as muscle stiffness, difficulty in movement, etc.
There are also some side-effects of unknown frequency, since it could not be measured by available data. Those effects involve heavy vomiting that can cause damage to the esophagus (the tube which connects mouth with the stomach), dehydration, liver function disorders (yellow coloration of the skin, sclera, noticeably dark urine or nausea, vomiting, fatigue and loss of appetite), aggressiveness, restlessness, and improper heart function.