Smart drugs, also called nootropics are brain function enhancing chemical drugs. They improve brain functioning and improve the quality of life in users. Having vast effects on memory, concentration, attention and cognition, these can be achieved to some extent by natural occurring foods as well but they don't compare to the superior efficacy of smart drugs. The following is the list of 6 such chemicals which have shown brain enhancing abilities
1. Modafinil (Provigil, Modalert) and Armodafinil (Nuvigil, Waklert)
Modafinil is a benzyl hydryl compound containing a sulphonyl group, it contains both the s- and r- enantiomers of Modafinil; Armodafinil contains only the r- enantiomer and is a refined version of the former. Both these compounds are ground breaking in their cognitive enhancing properties with very little potential for addiction. They basically increase histamine, dopamine, noradrenaline, serotonin and hypocretin in the brain, simultaneously reducing GABA levels. Now as the generic forms are also in the market they are easily available to buy online and are rather cheap as well. They help in improving focus and memory, also they give a clarity to thinking and due to its effects on serotonin also increase motivation with a positive effect on the mood.
2. Amphetamines (Adderall)
Amphetamine is central nervous system stimulant belonging to the sympathomimetics. It effects a much larger portion of the brain than Modafinil and is usualy used to increase focus and attention in conditions like attention deficit hyperactivity disorder. Apart from that it causes euphoria and promotes wakefulness; in some places it has also been used as an aphrodisiac. Like Modafinil it increases dopamine and noradrenaline however it does not effect any of the other neurochemicals like Modafinil. It helps both long and short term memory. The biggest drawback of amphetamines are its side effects specially the risk of addiction which has caused numerous legalities to be sanctioned on the use of amphetamines.
The active and addictive chemical found in cigarettes has been used for a long time and is known to increase focus and motivation and elevate mood. It refines motor skills, improves attention and short term memory and speeds up the reaction time. It exerts these effects by increasing mitochondrial energy which pretty much boosts the whole cell and in turn an organ. However as nicotine effects are short lasting and repeated administration is needed. One could use nicotine patching but even that gets hectic after a while. Also after much research on cigarettes nicotine has been found to harden the blood vessels in the heart and thus promote atherosclerosis. It increases blood pressure as well. The risk on cancer is the next thing to worry about even without the many harmful chemicals present in cigarettes.
This class of drug share pyrrolidone nucleus. Many have been made like piracetam, oxiracetam and phenylpircetam and are nootropic stimulants. Further classes like seletracetam and levetiracetam are used as anticonvulsants. Aniracetam is one of the most effective nootropic. Generally racetams improve mental turnover (processing speed), learning, memory and reduces stress as well. It has been known to improve confidence as its effects were noticed a lot in people taking them before public speaking whereby it increased fluency and improved overall delivery which has attracted a lot of people. Apart from their bitter taste they can cause headaches and much research is going on to make analog racetams which can be patented and sold.
5. LSD (Lysergic acid diethylamide)
This some what famous recreational and psychedelic drug has been used by many huge names since its discovery in 1943. Although it is not addictive it is still legally restricted due to its high potency and varying degrees of side effects. The nootropic dose is 1/10th of the normal recreational dose and it increases creativity, improves mood and focus and produces empathy as well. Again there are side effects like anxiety, panic attacks and one of the most troubling ones, hallucinations. On LSD people have been reported to get stuck in a 'bad trip' and eventually a form of psychosis wherein the personality of the user changes completely. But nootropic users say that on low doses it is safe however this isn't supported by any research or otherwise confirmed.
Probably the most widely substance throughout the world, the constituent of tea, coffee and some other drinks caffeine is a central nervous system stimulant. It belongs to the methylxanthine class which prominently and reversibly blocks the adenosine receptors in the brain. It reduces fatigue and drowsiness, whereby improving reaction time, concentration, wakefulness and motor coordination. Most of all it is easily and widely available as unlike other nootropics it isn't regulated by any legality throughout the world. It effects are short lived and one usually has to take it multiple times per day to produce the required effect. Excess of everything being bad it has a tendency for addiction and tolerance does develop to it and people have reported some withdrawal symptoms upon discontinuation.
Other notable mentions include:
- L-theanine (a component of black and green tea);
- Bacopa Monnieri (small water plant in India);
- Unfair advantage;
- Forskolin and Artichoke extract;
Nootropics are breakthrough medicines used by a vast majority who want to excel, underachievers who want to perform. They have their side effects but when taken under the guidance of a health professional and appropriate doses they can do wonders and help one achieve part of the impossible. Modafinil which is available to buy online is by far the most latest and effective cognitive enhancer in the list. Its newer derivative form Armodafinil is even better and also cheaper than the former. It is also superior as it has less side effects and again very little addiction potential. Thousands of people have been using these various nootropics for many years without any troublesome side effects but again dosage and frequency should be monitored carefully as there is a thin line when it comes to cognitive enhancers and it is vital to stay on the positive side of their effects.