11 Jun 2017
Excellent based on 10 reviews
1 inh @ $52.66 per inh
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General Info: Uses and Effects
Atrovent Generic contains an active substance called Ipratropio Bromuroe. Clinical research has shown that Atrovent exhibits anticholinergic effects (parasimpatolytic effects) and inhibits reflexes mediated by the nervous vagus by blocking the action of acetyl choline.
Bronchodilation (widening of bronchi) after the Atrovent inhalation is primarily local and comes from the lungs. The systemic effects of this drug are not responsible for bronchodilatory properties.
Atrovent has a total clearance of 2.3L/min while renal clearance is 0.9L/min. After inhalation, as much as 89% are metabolized in the liver by oxidation processes, and only 3.2% of the drug is excreted in the urine.
Atrovent is used to treat bronchospasm (narrowing of the bronchi) in adult patients with chronic obstructive pulmonary disease.
Efficacy of Atrovent in alleviating the symptoms of chronic obstructive pulmonary disease has been demonstrated in two double-blind, randomized, placebo-controlled studies. These two studies included approximately 1000 men and women over the age of 40 who had a positive diagnosis of chronic obstructive pulmonary disease. These patients were divided into two groups: one group was taking Atrovent and the other group was taking placebo. At the end of the study, the results showed a significant improvement in the symptoms in the group that was taking Atrovent compared to the placebo group.
Contraindications: Important to Know
Atrovent is absolutely contraindicated in patients who are allergic to the active substance Ipratropio Bromuroe or Atropine. If you notice symptoms of the following allergic reactions (facial edema, swelling of the tongue, difficulty swallowing, shortness of breath, or chest pain), you should immediately contact your doctor.
Atrovent is a medicine that is primarily used for the treatment of bronchospasm associated with chronic obstructive lung disease and should not be used in the treatment of acute asthma attacks.
Keep in mind that you must avoid contact with the eyes because there is a possibility of eye irritation that may impair your vision. Atrovent may also increase eye pressure and lead to glaucoma. Patients that have glaucoma should not use this medicine without prior consultation with the doctor.
Effects of Atrovent last for an average of 2-4 hours. You should never increase the dose of the drug without prior consultation with the doctor. Taking higher doses will not prolong the effect of this medicine but will increase your risk of side effects.
Safety and efficacy of Atrovent in pediatric population has not been established and its use should be avoided in children.
Since Atrovent exhibits anticholinergic properties, it can very often cause narrow angle glaucoma, mydriasis, acute eye pain, urinary retention, paradoxical spasm of bronchi, hypotension, and constipation. Immediately contact your doctor if you notice any side effects.
Instructions on Taking
Atrovent should be administered with the Atrovent HFA Inhalation Aerosol mouthpiece. This mouthpiece should not be used with other medications. Atrovent canister should be thrown out when the predicted number of inhalations indicated on the label have been used.
Detailed process of using Atrovent is described below:
- Insert the metal canister into the clean end of the mouthpiece, and make sure that the metal canister is firmly attached to the mouthpiece.
- Move away the protective cap (which usually has green color).
- Expire all air through your mouth. Hold the metal canister between the thumb and the first two fingers. Insert the mouthpiece in your mouth and close your mouth. Close your eyes to avoid contact with eyes.
- Start to breathe slowly and deeply and at the same time gently press the metal canister to relieve the dose of the drug.
- Hold the breath for 10-20 seconds and then eject the mouthpiece from your mouth.
- Wait for 20 seconds and repeat the procedure.
It is very essential to keep the mouthpiece clean because this part can be blocked, which may cause inadequate dosing.
Atrovent is intended for inhalation and is administered with the appropriate inhalation spray device.
Patients who administer Atrovent often report a taste disorder, but this should not interfere with the regular administration of this drug.
Atrovent comes in the form of an aerosol and you don't have to shake it before use. The usual starting dose is two inhalations of this drug four times a day (every 6 hours). If necessary, the dosage may be increased, but it should not exceed 12 inhalations per day.
Atrovent may lead to the following side effects:
- Infections affecting the upper respiratory tract;
- Influenza-like symptoms;
- Urinary tract infections;
- Atrial fibrillation;
- Allergic reactions;
- Dry mouth;
- Back pain;
Interactions with Other Drugs
There are 366 known interactions of Atrovent with other drugs.
Atrovent can interact with the following medicines:
- Clemastine - a drug used to treat allergies. The concomitant use with this medicine may result in blurred vision, dry mouth, decreased sweating, cramps in the stomach, tachycardia, glaucoma, and memory disorders.
- Dexbrompheniramine - a drug that is used for the treatment of urticaria. The simultaneous administration can result in difficulty in urinating and difficulty breathing.
- Diphenhydramine - a drug that is used to treat allergic rhinitis. The contemporary use may lead to confusion, decreased sweating, rapid heart rate, and difficulty breathing.
- Chlorpheniramine - the first generation antihistamine agent used in the treatment of rhinitis and urticaria. The contemporary administration increases the risk of adverse effects.
- Hyoscyamine - a drug that is used to treat bladder spasms, irritable bowel syndrome, gastric ulcer, and pancreatitis. The simultaneous administration should be avoided due to an increased risk of side effects.
- Amitriptyline - a drug that is used to treat depression. The simultaneous administration with this medicine may lead to memory impairment, difficulty urinating and tachycardia.
- Acrivastine - a drug that is used to treat hay fever and urticaria. The concomitant use increases the risk of glaucoma.
- Aclidinium bromide - a long-acting muscarine antagonist used in the treatment of chronic obstructive pulmonary disease. The concomitant use can lead to side effects.
- Acetylcholin eye drops. The contemporary administration can reduce the effects of both drugs.
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