About paxil-paroxetine

General Info: Uses and Effects

Paxil Generic (Paroxetine) is an oral medicine for the treatment of depression, social anxiety disorder, premenstrual dysphoric malady, PTSD and obsessive-compulsive disorder (OCD). This drug is an antidepressant in a class of medicaments known as selective serotonin reuptake inhibitors (SSRIs), which is a group that also contains sertraline (Zoloft), citalopram (Celexa), and fluoxetine (Prozac).

Paxil Generic works by affecting the chemicals in a person's brain that might be unbalanced in a person with anxiety, depression, or other related disorders. The chemicals are called neurotransmitters, which the brain's nerves manufacture and release. Neurotransmitters travel and attach themselves to other nearby nerves. The nerves use these chemicals to coordinate and communicate with one another. It goes without saying that neurotransmitters are the brain's communication system.

Serotonin is one of the neurotransmitters that travel across the spaces that exist between the nerves. They attach themselves to the receptors on the surfaces of the nearby nerves that produce and release them. The nerve takes up serotonin before releasing it again. This process is known as re-uptake. If an imbalance exists among serotonin, then an individual is likely to suffer from depression.

Paroxetine prevents the re-uptake of serotonin by the nerve cells. This means that there will be an increased amount of free serotonin which stimulates the nerve cells in a person's brain.

Even though Paxil Generic is approved by FDA, it is a prescription medicine. You must consult your doctor before you take these pills.

Contraindication: Important to Know

It is paramount to inform your doctor about your medical history, allergic reactions to certain foods and medications, and your current health issues. Yes, the tablet is licensed for the doctors to prescribe it to patients. However, you must first inform your doctor before taking it. The following groups of people shouldn't take Paroxetine:

  • People with recent heart attack or stroke;
  • Patients who are currently under Monoamine Oxidase Inhibitors;
  • People who stopped using Monoamine Oxidase Inhibitors 14 years ago;
  • Individuals with kidney disease;
  • Hypertensive individuals.

You must tell your doctor if you are using any supplements and medications. If you are a woman, you should inform your doctor immediately if you are tested positive for pregnancy.

Instructions on Taking

Paxil Generic is a prescription drug, and patients must follow the instruction on its label. You must not take this medicine before consulting the doctor. Otherwise, you might experience severe complications. You must also stick to the recommended amount as per the direction of your doctor. Precisely, you must not take either smaller or larger amount of the drug.

You should swallow Paroxetine whole without chewing or crushing it. Furthermore, you should not break an extended-release Paxil Generic tablet. The oral suspension must be shaken well before the patient measures a dose. To ensure that you are taking the recommended amount, use a special doses-measuring spoon or dosing syringe to measure your liquid medicine. The symptoms might take up to about a month to start improving.

Take this drug by mouth either with or with no food depending on the prescription of your doctor. Sometimes, taking this medication with food decreases nausea.


The recommended dosage of this medicine depends majorly on the disorder being treated. The initial dosages usually range from 20mg to 50mg per day. Paroxetine should be taken once a day in the morning.

For adults, the recommended starting dose for oral tablet is 20mg once a day. The doctor will start increasing the dose for you with time depending on the effectiveness of the medicine on you. The dosage increment is usually 10mg once a day after every seven days. The maximum dose should be 50mg in a day.

You should not stop taking Paxil Generic suddenly because it may make withdrawal symptoms become severe. Follow the instructions of your doctor when taking this medicine. The drug is potentially dangerous if you start using it without the prescription of a specialist or a physician.

Side Effects

Most medications have side effects on patients. On the same note, there are side effects of Paxil Generic (Paroxetine). In more often than not, the adverse effects of this drug are usually different from one individual to another. Fortunately, the side effects are usually mild and brief. The following are some of the most common side effects that patients may experience:

  • Dry mouth;
  • Nasal irritation;
  • Constipation;
  • Drowsiness;
  • Yawning;
  • Headache;
  • Dizziness;
  • Restlessness;
  • Weight changes;
  • Sleep problems;
  • Nervousness.

Other serious side effects that maybe observed include:

  • Nausea;
  • Ringing in a patient's ear;
  • Decreased sex drive;
  • Unusual skin reaction;
  • Hallucination, agitation;
  • High fever, stiff muscles, overactive reflexes and fast heartbeats.

Call your doctor right away if you experience any of the above serious effects. It's not advisable to use this pill routinely because you might become dependent on it.

Interaction with Other Drugs

Paxil Generic (Paroxetine) usually interacts with the following medicines:

  • Blood thinners;
  • Heart medications;
  • Medicines for treating psychiatric disorders;
  • Rizatriptan;
  • Naratriptan;
  • Sumatriptan;
  • Frovatriptan;
  • Almotriptan;
  • L-tryptophan;
  • Theophylline;
  • Tamoxifen;
  • St. John's wort;
  • Ritonavir;
  • Fosamprenavir;
  • Fentanyl;
  • Cimetidine;
  • AIDS medications.

The drug may also interact with allergy medicines, muscle relaxers, medicines for anxiety or seizures, narcotics and sedatives. Other medicines that tend to react with Paroxetine are anti-inflammatory and nonsteroidal tablets.