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General Info: Uses and Effects
Tetracycline produced under the generic name Sumycin is one of the safest and effective forms of oral antibiotics. Just like most bactericidal tablets in its category, Tetracycline is a broad spectrum antibiotic. It's also highly effective against different infections like acne, brucellosis, syphilis, malaria, influenza, gonorrhea, chlamydia, and other sexually transmitted diseases.
Patented in 1953 and produced commercially in 1978, this drug is one of the most effective and safe pills to use. Most times, it's usually available as a generic medication. Sumycin is a broad-spectrum antibiotic, and this is evident in its bacteriostatic activity against aerobic and aerobic bacteria.
Tetracycline's mechanism of action is based on inhibiting the production of protein in some many micro-organisms. It's no surprise that this is the first line of treatment for Lyme disease, P fever, Rocky Mountain spotted fever, and chlamydia.
Although, most pathogenic organisms have developed acquired resistance to the effects of Tetracycline, resistance against Enterobacteriaceae, streptococcus, and Neisseria gonorrhea is now common. Also, exotic diseases like Rickettsia and Lyme disease are susceptible to this drug.
Contraindication: Important to Know
Just like most broad-spectrum antibiotics, Sumycin causes allergic reactions or hypersensitivity in those allergic to Penicillin or Cephalosporin-type of antibiotics. So, it's not uncommon to see symptoms of allergic reactions like rash, facial edema, and itchy skin. It is best advised to consult a physician before undergoing the Tetracycline treatment.
Sumycin is fatal for pregnant women since it can cross via the placenta to wreak havoc on the unborn child; in fact, there have been high levels of embryotoxicity in pregnant women who used this medicine. Besides, it's been known to retard the skeletal development of newborns.
Furthermore, this drug causes enamel hyperplasia in both unborn and newborn kids. As mentioned earlier, Tetracycline travels via the placenta and causes permanent discoloration of the teeth of the newborn.
Therefore, nursing mothers and pregnant women should stay away from Sumycin during the later phase of pregnancy, or the early years of the infant child. Tetracycline should only be used in cases where other drugs are not likely to be effective.
Instructions on Taking
Sumycin is more than just antibiotics, as it requires a recommendation from a doctor before it's used. In fact, the pill is only used in the presence of a strong bacterial infection. This is to prevent the incidence of drug-resistant bacterial infections. Additionally, there's also a chance of super-infection caused by the uninhibited growth of fungi and other microflora.
Recent studies have also shown a correlation between Tetracycline and benign intracranial hypertension. This illness is usually preceded by symptoms of a headache and blurred or double vision. Using this medicine is one of the primary causes of bulging fontanels in children, as there have been reports in the reduction in the size of the fontanel when tetracycline is withdrawn.
Those with allergies, urticaria, hay fever, and asthma should consult their doctor before using this drug. Furthermore, nursing mothers are advised to use alternative antibiotics, since Sumycin has an adverse effect on newborns. In fact, it is usually the last recommendation for nursing mothers.
Lastly, under no circumstances should you use expired Tetracycline. The degradation of this medicament after expiration is nephrotoxic, and it induces a Franconi-like syndrome.
Dosage instruction for Sumycin is based on different factors: age, infections, and body weight. So, it's ideal to always ask for medical advice before using this medicine.
For adults, about 1 to 2g of Tetracycline is usually prescribed. About 500mg per day is prescribed for mild infections, while doses above 500mg are prescribed for severe infections. 10 to 20mg is prescribed for children above eight years with body weight less than 50kg. You should ensure the medication continues about 24 hours after the symptoms or fever has subsided.
500mg of Sumycin should be administered four times daily for the treatment of brucellosis. This should be accompanied by 1g of intramuscularly applied streptomycin. In cases of streptococcal infections, a therapeutic dose of the tablet should be administered for ten days.
Like most antibiotics, Tetracycline is responsible for various hypersensitivity reactions, such as serum-like reactions, urticaria, rashes, anaphylactoid purpura, edema, and pericarditis.
It is also responsible for gastrointestinal problems like inflammatory lesions, epigastric distress, loose stools, anorexia, stomatitis, black hairy tongue, stomatitis, nausea, glossitis, vomiting, diarrhea, hoarseness, dysphagia, and enterocolitis. These reactions are usually associated with oral administration of the drug.
Sumycin has also been associated with skin diseases like dermatitis, discoloration of the nail (onycholysis), and photosensitivity. Also, some users of this drug have reported an increase in the incidence of sunburn due to the overly sensitive skin.
Interaction with Other Drugs
Bacteriostatic drugs like Tetracycline may interfere with the effects of Penicillin which is a bactericidal drug. Therefore, it's advisable to stop one medication before using the other.
Additionally, Sumycin can suppress plasma prothrombin activity. So, patients on anticoagulant therapy should consult their doctor before using it. Lastly, this drug interferes with the effectiveness of oral contraceptives.