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General Info: Uses and Effects
Zyprexa Generic (Olanzapine) is a prescription drug made into a tablet form for oral administration. It also has the disintegrating tablet, which is soluble upon contact with the mouth. Besides, has the intravenous form administered only by physicians.
Zyprexa is a renown medication for treating schizophrenia and bipolar I disorder. It is taken alongside Fluoxetine to correct other ailments. These disease conditions are depression arising from bipolar I disorder and depression beyond the power of other medications.
Olanzapine is classed among the less common antipsychotics. Drugs are graded based on similarities in their mode of action. Antipsychotic drugs are mostly used to treat psychiatric conditions.
How Zyprexa Olanzapine works is not known. However, there are impressions that it might aid in regulating the level of some chemicals like dopamine and serotonin in the brain to regulate the mood.
Contraindications: Important to Know
Patients with records of hypersensitivity to Olanzapine should never use the Zyprexa tablet and similarly, if you are hypersensitive to other condiments of the medication, do not take the drug. Allergic symptoms can manifest as a rash, puffed dace, Dyspnea, and swollen lips. If you're experiencing this, inform your physician.
Speak to your doctor or pharmacist before you use the Olanzapine tablets. Old people diagnosed with dementia are highly discouraged from taking this drug as it may give serious side effects. Drugs of this class can trigger strange movements majorly in the orofacial region. If there is the case after using Zyprexa, inform your physician
Less often, the drug of this class induces a blend of fever, difficulties in breathing, sweating, muscle immobility, dizziness, and fainting spells. Should this happen, alert your physician immediately. Increase in weight is also one of the aftermaths of using the Olanzapine tablets. It is therefore necessary that you watch your weight at intervals while you are on the drug.
Another thing you need to watch while using these tablets is your blood sugar level, and those of fats as the drug can raise their levels in the body. It is essential that your physician conduct blood tests to determine the level of sugar in your blood and the level of some fat in your body before you can begin to use Zyprexa.
Inform your physician if you or another individual in your family has a known record of hemophilia as this class of drugs have been linked to the development of blood clots. Peradventure you have any of these ailments, notify your physician immediately: paralysis of specific body parts, Parkinson's disease, prostate disorders, liver or renal impairment, blood ailments, cardiac disorders, diabetes, and seizures.
Perhaps you have dementia, you or your aid need to notify your physician if you have had a history of stroke or mini-stroke. It is good practice that patients above 65 years of age have their blood pressure watched while using Olanzapine.
Do not use other drugs alongside the Olanzapine tablets until your physician has certified that you really can. You might experience some dizziness should you use these tablets alongside antidepressants or other sleep-inducing drugs.
Inform your physician if you're using or you've recently used, or you might likely use other drugs. Especially, notify your doctor if you are using medications for Parkinson's disease. Carbamazepine, Fluvoxamine or Ciprofloxacin as it might be needful to alter the dosage of Zyprexa.
Instructions on Taking
Endeavor to use this drug just as directed by your physician. Contact your doctor or pharmacist if you're not very sure about it. Your physician will inform you of the amount of the Olanzapine tablets to be taken and the duration of time to keep using them.
The recommended dose to be used in a day is around 5mg to 20mg. Contact your physician if you have a relapse of the symptoms but never should you stop using the Olanzapine tablets unless otherwise directed by your physician. It is important you use your Zyprexa Generic daily as instructed by your physician.
Make sure you use this drug at about the same time every day. You can take Zyprexa with or without food. This drug is available for oral administration as tablets which can break easily, as such, a measure of caution need be exercised in its handling. Never hold the medication with wet hands as the tablets might break up.
Ensure that your hand is kept dry and never draw the tablet out of your pocket. Then, place the drug into your mouth for direct dissolution. You can equally dissolve the tablet in a cup of water, fruit juice, or milk and mix evenly. It could give a color change and cloudiness, just take it immediately.
For adults who have schizophrenia, the advisable starting dose for Zyprexa Generic is 10mg daily. For manic disorders however the starting dose is 15mg to be taken once or 10mg to be taken two times daily. To avoid a relapse of bipolar disorder, the dosage recommended for a start is 10mg daily.
In patients who have been taking Olanzapine for mania, keep using the drug to prevent a relapse maintaining the same dosage. While treating schizophrenia, mania and decline prevention in bipolar disorder, the daily dosage can be adjusted based on the patient's reactions between 5mg to 20mg daily.
You may not increase the dose to a higher value than the advised starting dose, except adequate clinical evaluation has been carried out, and of course, this increment should not be less than 24 hours to the commencement. You can use Olanzapine irrespective of whether or not you have eaten as its metabolism is not affected by food.
Just like all other drugs, Zyprexa Olanzapine can give side effects, although the manifestation varies with individuals. Notify your physician immediately if you perceive strange movements majorly in your face or tongue, thrombosis in the lower limb that may communicate with the blood vessels of the lung, causing dyspnea and chest pains.
If you notice any of this, contact your physician immediately: a mix of fever, accelerated breathing, profuse sweating, muscle stiffness and dizziness, or feeling tipsy. The more common adverse effects include increased weight, fainting spells, and high level of blood prolactin. When starting the treatment, some patients might be dizzy or even faint and experience arrhythmia, especially when rising from a supine position. This should fade out on its own, however, if it persists, contact your physician.
Other side effects are noticeable changes in the percent volume count PCV value of the blood, body fat and in some cases, short-term increase in liver enzymes, sugar levels in the blood and urine, amount of uric acid in the body and those of creatine phosphokinase in the blood.
Interaction with Other Drugs
As Olanzapine is metabolized by CYP1A2, the substances that can particularly trigger or retard this isoenzyme can impact on the pharmacokinetics of Zyprexa. The metabolism of this drug can further be disrupted by smoking and carbamazepine, which can cause lower Olanzapine levels in the body.
Fluvoxamine, a particular inhibitor, can interact with Zyprexa and retard the metabolism. Activated charcoal lowers the bioavailability of oral Olanzapine by more than half and ought not to be taken together with the drug.
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